Timothy M . Frayling , Childhood and Adult Obesity with Body Mass Index and Predisposes to Gene Is AssociatedFTOA
نویسنده
چکیده
http://www.sciencemag.org/cgi/content/full/316/5826/889 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/1141634/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://www.sciencemag.org/cgi/content/full/316/5826/889#related-content http://www.sciencemag.org/cgi/content/full/316/5826/889#otherarticles , 7 of which can be accessed for free: cites 18 articles This article 42 article(s) on the ISI Web of Science. cited by This article has been http://www.sciencemag.org/cgi/content/full/316/5826/889#otherarticles 21 articles hosted by HighWire Press; see: cited by This article has been http://www.sciencemag.org/cgi/collection/genetics Genetics : subject collections This article appears in the following
منابع مشابه
Commentary: A new dawn for genetic epidemiology?
2003;32:1–22. 4 Frayling TM, Timpson NJ, Weedon MN et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007;316:89–94. 5 Dina C, Meyre D, Gallina S et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007;39:724–26. 6 Brennan P, McKay J, Moore L et al. Uncommon CHEK2 mis-sense...
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Obesity is a serious international health problem that increases the risk of several common diseases. The genetic factors predisposing to obesity are poorly understood. A genome-wide search for type 2 diabetes-susceptibility genes identified a common variant in the FTO (fat mass and obesity associated) gene that predisposes to diabetes through an effect on body mass index (BMI). An additive ass...
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